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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | D(1B) dopamine receptor | ||
| Ligand | BDBM50088341 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_453888 (CHEMBL885890) | ||
| Ki | 7.5±n/a nM | ||
| Citation |  Enzensperger, C; Kilian, S; Ackermann, M; Koch, A; Kelch, K; Lehmann, J Dopamine/serotonin receptor ligands. Part 15: Oxygenation of the benz-indolo-azecine LE 300 leads to novel subnanomolar dopamine D1/D5 antagonists. Bioorg Med Chem Lett17:1399-402 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| D(1B) dopamine receptor | |||
| Name: | D(1B) dopamine receptor | ||
| Synonyms: | D(5) dopamine receptor | D1beta dopamine receptor | DOPAMINE D5 | DRD1B | DRD1L2 | DRD5 | DRD5_HUMAN | dopamine receptor D5 | ||
| Type: | Protein | ||
| Mol. Mass.: | 52943.41 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P21918 | ||
| Residue: | 477 | ||
| Sequence: |
| ||
| BDBM50088341 | |||
| n/a | |||
| Name | BDBM50088341 | ||
| Synonyms: | 11-methyl-11,21-diazatetracyclo[12.7.0.0^{3,8}.0^{15,20}]henicosa-1(14),3(8),4,6,15,17,19-heptaene | 7-Methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]-benzazecine | 7-methyl-6,7,8,9,14,15-hexahydro-5H-benzo[7,8]azecino[5,4-b]indole(LE 300) | 7-methyl-6,7,8,9,14,15-hexahydro-5H-indolo[3,2-f][3]benzazecine | CHEMBL441618 | LE 300 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C20H22N2 | ||
| Mol. Mass. | 290.4021 | ||
| SMILES | CN1CCc2c(Cc3ccccc3CC1)[nH]c1ccccc21 | ||
| Structure | 
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