| Reaction Details |
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 | Report a problem with these data |
| Target | Cathepsin S |
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| Ligand | BDBM50201702 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_438178 (CHEMBL907571) |
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| IC50 | 696±n/a nM |
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| Citation |  Epple, R; Urbina, HD; Russo, R; Liu, H; Mason, D; Bursulaya, B; Tumanut, C; Li, J; Harris, JL Bicyclic carbamates as inhibitors of papain-like cathepsin proteases. Bioorg Med Chem Lett17:1254-9 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cathepsin S |
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| Name: | Cathepsin S |
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| Synonyms: | CATS_HUMAN | CTSS | Cathepsin S (Cat S) | cathepsin S preproprotein |
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| Type: | Protein |
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| Mol. Mass.: | 37507.38 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P25774 |
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| Residue: | 331 |
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| Sequence: | MKRLVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVM
LHNLEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVD
WREKGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGC
NGGFMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKE
AVANKGPVSVGVDARHPSFFLYRSGVYYEPSCTQNVNHGVLVVGYGDLNGKEYWLVKNSW
GHNFGEEGYIRMARNKGNHCGIASFPSYPEI
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| BDBM50201702 |
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| n/a |
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| Name | BDBM50201702 |
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| Synonyms: | (1R,2S)-2-phenoxy-7-oxa-5-aza-bicyclo[3.2.1]octane-6-thione | CHEMBL390643 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H13NO2S |
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| Mol. Mass. | 235.302 |
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| SMILES | S=C1O[C@@H]2CN1CC[C@@H]2Oc1ccccc1 |
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| Structure | 
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