| Reaction Details |
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 | Report a problem with these data |
| Target | Vasopressin V1a receptor |
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| Ligand | BDBM50202890 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_441650 (CHEMBL891881) |
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| Ki | 13.3±n/a nM |
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| Citation |  Guillon, CD; Koppel, GA; Brownstein, MJ; Chaney, MO; Ferris, CF; Lu, SF; Fabio, KM; Miller, MJ; Heindel, ND; Hunden, DC; Cooper, RD; Kaldor, SW; Skelton, JJ; Dressman, BA; Clay, MP; Steinberg, MI; Bruns, RF; Simon, NG Azetidinones as vasopressin V1a antagonists. Bioorg Med Chem15:2054-80 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Vasopressin V1a receptor |
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| Name: | Vasopressin V1a receptor |
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| Synonyms: | AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor |
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| Type: | Receptor |
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| Mol. Mass.: | 46820.18 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P37288 |
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| Residue: | 418 |
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| Sequence: | MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAV
TFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGP
DWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFV
LSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFIC
YNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAY
IVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCV
QSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
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| BDBM50202890 |
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| n/a |
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| Name | BDBM50202890 |
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| Synonyms: | 4-amino-1-benzyl-1-{2-[(3S,4R)-2-oxo-3-[(4S)-2-oxo-4-phenyl-1,3-oxazolidin-3-yl]-4-[(E)-2-phenylethenyl]azetidin-1-yl]-2-({[3-(trifluoromethyl)phenyl]methyl}carbamoyl)acetyl}piperidin-1-ium | CHEMBL389139 |
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| Type | Small organic molecule |
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| Emp. Form. | C43H43F3N5O5 |
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| Mol. Mass. | 766.8267 |
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| SMILES | n/a |
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| Structure | 
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