| Reaction Details |
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 | Report a problem with these data |
| Target | Carbonic anhydrase 14 |
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| Ligand | BDBM26996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_458929 (CHEMBL924948) |
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| Ki | 92000±n/a nM |
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| Citation |  Innocenti, A; Vullo, D; Pastorek, J; Scozzafava, A; Pastorekova, S; Nishimori, I; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of transmembrane isozymes XII (cancer-associated) and XIV with anions. Bioorg Med Chem Lett17:1532-7 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Carbonic anhydrase 14 |
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| Name: | Carbonic anhydrase 14 |
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| Synonyms: | CA-XIV | CA14 | CAH14_HUMAN | Carbonate dehydratase XIV | Carbonic Anhydrase XIV | Carbonic anhydrase | Carbonic anhydrase 14 | Carbonic anhydrase 14 (CA XIV) | Carbonic anhydrase XIV (CA XIV) |
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| Type: | Enzyme |
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| Mol. Mass.: | 37665.67 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Human (cloned) isozyme. |
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| Residue: | 337 |
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| Sequence: | MLFSALLLEVIWILAADGGQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPD
LPALQPHGYDQPGTEPLDLHNNGHTVQLSLPSTLYLGGLPRKYVAAQLHLHWGQKGSPGG
SEHQINSEATFAELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSH
LHEVRHKDQKTSVPPFNLRELLPKQLGQYFRYNGSLTTPPCYQSVLWTVFYRRSQISMEQ
LEKLQGTLFSTEEEPSKLLVQNYRALQPLNQRMVFASFIQAGSSYTTGEMLSLGVGILVG
CLCLLLAVYFIARKIRKKRLENRKSVVFTSAQATTEA
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| BDBM26996 |
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| n/a |
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| Name | BDBM26996 |
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| Synonyms: | CHEMBL21485 | PhB(OH)2 | Phenyl-boronic acid | Phenylboronic acid, 22 | benzeneboronic acid | phenylboranediol | phenylboronic acid |
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| Type | n/a |
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| Emp. Form. | C6H7BO2 |
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| Mol. Mass. | 121.93 |
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| SMILES | OB(O)c1ccccc1 |
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| Structure | 
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