| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2b |
|---|
| Ligand | BDBM50205286 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_425914 (CHEMBL907369) |
|---|
| Ki | 300±n/a nM |
|---|
| Citation |  Chang, LC; von Frijtag Drabbe Künzel, JK; Mulder-Krieger, T; Westerhout, J; Spangenberg, T; Brussee, J; Ijzerman, AP 2,6,8-trisubstituted 1-deazapurines as adenosine receptor antagonists. J Med Chem50:828-34 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2b |
|---|
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36341.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 332 |
|---|
| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
|
|
|
|---|
| BDBM50205286 |
|---|
| n/a |
|---|
| Name | BDBM50205286 |
|---|
| Synonyms: | 8-cyclopentyl-2,6-diphenyl-1-deazapurin | CHEMBL219625 | LUF-5816 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H21N3 |
|---|
| Mol. Mass. | 339.4329 |
|---|
| SMILES | C1CCC(C1)c1nc2c(cc(nc2[nH]1)-c1ccccc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
