| Reaction Details |
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 | Report a problem with these data |
| Target | C-C chemokine receptor type 5 |
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| Ligand | BDBM50205738 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_428417 (CHEMBL919487) |
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| IC50 | 49000±n/a nM |
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| Citation |  Kellenberger, E; Springael, JY; Parmentier, M; Hachet-Haas, M; Galzi, JL; Rognan, D Identification of nonpeptide CCR5 receptor agonists by structure-based virtual screening. J Med Chem50:1294-303 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| C-C chemokine receptor type 5 |
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| Name: | C-C chemokine receptor type 5 |
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| Synonyms: | C-C CKR-5 | C-C chemokine receptor type 5 | CC-CKR-5 | CCR-5 | CCR5 | CCR5/mu opioid receptor complex | CCR5_HUMAN | CD_antigen=CD195 | CHEMR13 | CMKBR5 | HIV-1 fusion coreceptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 40540.21 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P51681 |
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| Residue: | 352 |
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| Sequence: | MDYQVSSPIYDINYYTSEPCQKINVKQIAARLLPPLYSLVFIFGFVGNMLVILILINCKR
LKSMTDIYLLNLAISDLFFLLTVPFWAHYAAAQWDFGNTMCQLLTGLYFIGFFSGIFFII
LLTIDRYLAVVHAVFALKARTVTFGVVTSVITWVVAVFASLPGIIFTRSQKEGLHYTCSS
HFPYSQYQFWKNFQTLKIVILGLVLPLLVMVICYSGILKTLLRCRNEKKRHRAVRLIFTI
MIVYFLFWAPYNIVLLLNTFQEFFGLNNCSSSNRLDQAMQVTETLGMTHCCINPIIYAFV
GEKFRNYLLVFFQKHIAKRFCKCCSIFQQEAPERASSVYTRSTGEQEISVGL
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| BDBM50205738 |
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| n/a |
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| Name | BDBM50205738 |
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| Synonyms: | 2-(4-oxo-3-(3-(piperidin-1-yl)propyl)-3,4-dihydroquinazolin-2-ylthio)-N-phenethylacetamide | CHEMBL426385 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H32N4O2S |
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| Mol. Mass. | 464.623 |
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| SMILES | O=C(CSc1nc2ccccc2c(=O)n1CCCN1CCCCC1)NCCc1ccccc1 |
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| Structure | 
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