| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50206595 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_428724 (CHEMBL915240) |
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| Ki | 497±n/a nM |
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| Citation |  Prezzavento, O; Campisi, A; Ronsisvalle, S; Li Volti, G; Marrazzo, A; Bramanti, V; Cannavò, G; Vanella, L; Cagnotto, A; Mennini, T; Ientile, R; Ronsisvalle, G Novel sigma receptor ligands: synthesis and biological profile. J Med Chem50:951-61 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50206595 |
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| n/a |
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| Name | BDBM50206595 |
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| Synonyms: | CHEMBL386002 | methyl (1R,2S/1S,2R)-1-(4-methylphenyl)-2-[(4-pyridin-2-ylpiperazin-1-yl)methyl]cyclopropanecarboxylate |
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| Type | Small organic molecule |
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| Emp. Form. | C22H27N3O2 |
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| Mol. Mass. | 365.4687 |
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| SMILES | COC(=O)C1(CC1CN1CCN(CC1)c1ccccn1)c1ccc(C)cc1 |
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| Structure | 
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