| Reaction Details |
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 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 5 |
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| Ligand | BDBM50209184 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_443470 (CHEMBL893728) |
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| Kd | 7560±n/a nM |
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| Citation |  Wendt, MD; Sun, C; Kunzer, A; Sauer, D; Sarris, K; Hoff, E; Yu, L; Nettesheim, DG; Chen, J; Jin, S; Comess, KM; Fan, Y; Anderson, SN; Isaac, B; Olejniczak, ET; Hajduk, PJ; Rosenberg, SH; Elmore, SW Discovery of a novel small molecule binding site of human survivin. Bioorg Med Chem Lett17:3122-9 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Baculoviral IAP repeat-containing protein 5 |
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| Name: | Baculoviral IAP repeat-containing protein 5 |
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| Synonyms: | API4 | Apoptosis inhibitor 4 | Apoptosis inhibitor survivin | BIRC5 | BIRC5_HUMAN | IAP4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 16386.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_443470 |
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| Residue: | 142 |
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| Sequence: | MGAPTLPPAWQPFLKDHRISTFKNWPFLEGCACTPERMAEAGFIHCPTENEPDLAQCFFC
FKELEGWEPDDDPIEEHKKHSSGCAFLSVKKQFEELTLGEFLKLDRERAKNKIAKETNNK
KKEFEETAKKVRRAIEQLAAMD
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| BDBM50209184 |
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| n/a |
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| Name | BDBM50209184 |
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| Synonyms: | 4-(2,5-dichlorophenyl)-6-(2-hydroxy-5-isobutylphenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile | CHEMBL399196 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H18Cl2N2O2 |
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| Mol. Mass. | 413.297 |
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| SMILES | CC(C)Cc1ccc(O)c(c1)-c1cc(-c2cc(Cl)ccc2Cl)c(C#N)c(=O)[nH]1 |
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| Structure | 
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