| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosine-protein phosphatase non-receptor type 2 |
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| Ligand | BDBM50292294 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_434270 (CHEMBL918430) |
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| IC50 | >1000000±n/a nM |
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| Citation |  Vazquez, J; Tautz, L; Ryan, JJ; Vuori, K; Mustelin, T; Pellecchia, M Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors. J Med Chem50:2137-43 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosine-protein phosphatase non-receptor type 2 |
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| Name: | Tyrosine-protein phosphatase non-receptor type 2 |
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| Synonyms: | PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP) |
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| Type: | Protein |
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| Mol. Mass.: | 48481.80 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P17706 |
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| Residue: | 415 |
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| Sequence: | MPTTIEREFEELDTQRRWQPLYLEIRNESHDYPHRVAKFPENRNRNRYRDVSPYDHSRVK
LQNAENDYINASLVDIEEAQRSYILTQGPLPNTCCHFWLMVWQQKTKAVVMLNRIVEKES
VKCAQYWPTDDQEMLFKETGFSVKLLSEDVKSYYTVHLLQLENINSGETRTISHFHYTTW
PDFGVPESPASFLNFLFKVRESGSLNPDHGPAVIHCSAGIGRSGTFSLVDTCLVLMEKGD
DINIKQVLLNMRKYRMGLIQTPDQLRFSYMAIIEGAKCIKGDSSIQKRWKELSKEDLSPA
FDHSPNKIMTEKYNGNRIGLEEEKLTGDRCTGLSSKMQDTMEENSESALRKRIREDRKAT
TAQKVQQMKQRLNENERKRKRWLYWQPILTKMGFMSVILVGAFVGWTLFFQQNAL
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| BDBM50292294 |
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| n/a |
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| Name | BDBM50292294 |
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| Synonyms: | 4-(5-((3-carboxy-4-hydroxyphenyl)amino)-5-oxopentanamido)-2,2,6,6-tetramethylpiperidin-1-olate | CHEMBL445152 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H30N3O6 |
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| Mol. Mass. | 420.4794 |
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| SMILES | CC1(C)CC(CC(C)(C)N1[O])NC(=O)CCCC(=O)Nc1ccc(O)c(c1)C(O)=O |^1:10| |
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| Structure | 
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