| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein phosphatase 3 |
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| Ligand | BDBM50292297 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_434272 (CHEMBL918432) |
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| IC50 | 850000±n/a nM |
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| Citation |  Vazquez, J; Tautz, L; Ryan, JJ; Vuori, K; Mustelin, T; Pellecchia, M Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors. J Med Chem50:2137-43 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein phosphatase 3 |
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| Name: | Dual specificity protein phosphatase 3 |
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| Synonyms: | DUS3_HUMAN | DUSP3 | Dual specificity protein phosphatase (VHR) | Dual specificity protein phosphatase 3 | Dual specificity protein phosphatase VHR | Protein Tyrosine Phosphatase VHR | Tyrosine-protein phosphatase non-receptor type 1 | VHR |
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| Type: | Hydrolase |
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| Mol. Mass.: | 20480.58 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 185 |
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| Sequence: | MSGSFELSVQDLNDLLSDGSGCYSLPSQPCNEVTPRIYVGNASVAQDIPKLQKLGITHVL
NAAEGRSFMHVNTNANFYKDSGITYLGIKANDTQEFNLSAYFERAADFIDQALAQKNGRV
LVHCREGYSRSPTLVIAYLMMRQKMDVKSALSIVRQNREIGPNDGFLAQLCQLNDRLAKE
GKLKP
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| BDBM50292297 |
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| n/a |
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| Name | BDBM50292297 |
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| Synonyms: | CHEMBL227608 | Methyl 2-hydroxy-5-(5-(((1-hydroxy-2,2,6,6-tetramethylpiperidin-4-yl)amino)methyl)furan-2-yl)benzoate |
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| Type | Small organic molecule |
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| Emp. Form. | C22H29N2O5 |
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| Mol. Mass. | 401.4761 |
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| SMILES | COC(=O)c1cc(ccc1O)-c1ccc(CNC2CC(C)(C)N([O])C(C)(C)C2)o1 |^1:23| |
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| Structure | 
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