| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1B |
|---|
| Ligand | BDBM50212044 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_436507 (CHEMBL904813) |
|---|
| Ki | 4.8±n/a nM |
|---|
| Citation |  Di Giacomo, B; Bedini, A; Spadoni, G; Tarzia, G; Fraschini, F; Pannacci, M; Lucini, V Synthesis and biological activity of new melatonin dimeric derivatives. Bioorg Med Chem15:4643-50 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1B |
|---|
| Name: | Melatonin receptor type 1B |
|---|
| Synonyms: | MTNR1B | MTR1B_HUMAN | Mel-1B-R | Mel1b melatonin receptor | Melatonin 1B | Melatonin receptor | Melatonin receptor type 1B | Melatonin receptor type 2 (MT2) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 40203.54 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P49286 |
|---|
| Residue: | 362 |
|---|
| Sequence: | MSENGSFANCCEAGGWAVRPGWSGAGSARPSRTPRPPWVAPALSAVLIVTTAVDVVGNLL
VILSVLRNRKLRNAGNLFLVSLALADLVVAFYPYPLILVAIFYDGWALGEEHCKASAFVM
GLSVIGSVFNITAIAINRYCYICHSMAYHRIYRRWHTPLHICLIWLLTVVALLPNFFVGS
LEYDPRIYSCTFIQTASTQYTAAVVVIHFLLPIAVVSFCYLRIWVLVLQARRKAKPESRL
CLKPSDLRSFLTMFVVFVIFAICWAPLNCIGLAVAINPQEMAPQIPEGLFVTSYLLAYFN
SCLNAIVYGLLNQNFRREYKRILLALWNPRHCIQDASKGSHAEGLQSPAPPIIGVQHQAD
AL
|
|
|
|---|
| BDBM50212044 |
|---|
| n/a |
|---|
| Name | BDBM50212044 |
|---|
| Synonyms: | CHEMBL390944 | pentyl 3-(2-acetamidoethyl)-5-methoxy-1Hindole-2-carboxylate |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H26N2O4 |
|---|
| Mol. Mass. | 346.4207 |
|---|
| SMILES | CCCCCOC(=O)c1[nH]c2ccc(OC)cc2c1CCNC(C)=O |
|---|
| Structure | 
|
|---|
Search and Browse
