| Reaction Details |
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 | Report a problem with these data |
| Target | Cannabinoid receptor 1 |
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| Ligand | BDBM50213617 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_456160 (CHEMBL888171) |
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| Ki | 2020±n/a nM |
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| Citation |  Kai, H; Morioka, Y; Murashi, T; Morita, K; Shinonome, S; Nakazato, H; Kawamoto, K; Hanasaki, K; Takahashi, F; Mihara, S; Arai, T; Abe, K; Okabe, H; Baba, T; Yoshikawa, T; Takenaka, H 2-Arylimino-5,6-dihydro-4H-1,3-thiazines as a new class of cannabinoid receptor agonists. Part 1: discovery of CB2 receptor selective compounds. Bioorg Med Chem Lett17:4030-4 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Cannabinoid receptor 1 |
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| Name: | Cannabinoid receptor 1 |
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| Synonyms: | Brain-type cannabinoid receptor | CANNABINOID CB1 | CB-R | CB1 | CNR1_MOUSE | Cannabinoid CB1 receptor | Cannabinoid receptor | Cnr1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52842.52 |
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| Organism: | Mus musculus (Mouse) |
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| Description: | P47746 |
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| Residue: | 473 |
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| Sequence: | MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
KMTAGDNSPLVPAGDTTNITEFYNKSLSSFKENEDNIQCGENFMDMECFMILNPSQQLAI
AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFVDFHV
FHRKDSPNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCL
MWTIAIVIAVLPLLGWNCKKLQSVCSDIFPLIDETYLMFWIGVTSVLLLFIVYAYMYILW
KAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPL
LAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTA
QPLDNSMGDSDCLHKHANNTASMHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
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| BDBM50213617 |
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| n/a |
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| Name | BDBM50213617 |
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| Synonyms: | (Z)-methyl 2-(2-isopropylphenylimino)-5,5-dimethyl-1,3-thiazinane-3-carbodithioate | CHEMBL232730 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H24N2S3 |
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| Mol. Mass. | 352.581 |
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| SMILES | CSC(=S)N1CC(C)(C)CS\C1=N/c1ccccc1C(C)C |
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| Structure | 
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