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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Gamma-aminobutyric acid receptor subunit beta-3 | ||
| Ligand | BDBM50214664 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_448071 (CHEMBL898326) | ||
| Ki | 0.659±n/a nM | ||
| Citation |  Alam, MS; Huang, J; Ozoe, F; Matsumura, F; Ozoe, Y Synthesis, 3D-QSAR, and docking studies of 1-phenyl-1H-1,2,3-triazoles as selective antagonists for beta3 over alpha1beta2gamma2 GABA receptors. Bioorg Med Chem15:5090-104 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Gamma-aminobutyric acid receptor subunit beta-3 | |||
| Name: | Gamma-aminobutyric acid receptor subunit beta-3 | ||
| Synonyms: | GABA A receptor alpha-4/beta-3/gamma-2 | GABA receptor beta-3 subunit | GABA-A receptor | GABRB3 | GBRB3_HUMAN | agonist GABA site | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 54130.51 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_448071 | ||
| Residue: | 473 | ||
| Sequence: |
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| BDBM50214664 | |||
| n/a | |||
| Name | BDBM50214664 | ||
| Synonyms: | 5-chloromethyl-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-n-propyl-1H-1,2,3-triazole | CHEMBL235623 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C13H11Cl3F3N3 | ||
| Mol. Mass. | 372.601 | ||
| SMILES | CCCc1nnn(c1CCl)-c1c(Cl)cc(cc1Cl)C(F)(F)F |(32.44,-26.02,;31.19,-25.11,;31.36,-23.58,;30.11,-22.67,;30.12,-21.13,;28.65,-20.65,;27.75,-21.9,;28.65,-23.14,;28.17,-24.61,;29.2,-25.75,;26.21,-21.89,;25.45,-23.23,;26.22,-24.56,;23.91,-23.23,;23.14,-21.89,;23.91,-20.56,;25.45,-20.56,;26.22,-19.23,;21.6,-21.89,;20.04,-21.96,;21.56,-20.35,;21.65,-23.43,)| | ||
| Structure | 
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