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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Gamma-aminobutyric acid receptor subunit beta-3 | ||
| Ligand | BDBM50214662 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_448071 (CHEMBL898326) | ||
| Ki | 7.1±n/a nM | ||
| Citation |  Alam, MS; Huang, J; Ozoe, F; Matsumura, F; Ozoe, Y Synthesis, 3D-QSAR, and docking studies of 1-phenyl-1H-1,2,3-triazoles as selective antagonists for beta3 over alpha1beta2gamma2 GABA receptors. Bioorg Med Chem15:5090-104 (2007) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Gamma-aminobutyric acid receptor subunit beta-3 | |||
| Name: | Gamma-aminobutyric acid receptor subunit beta-3 | ||
| Synonyms: | GABA A receptor alpha-4/beta-3/gamma-2 | GABA receptor beta-3 subunit | GABA-A receptor | GABRB3 | GBRB3_HUMAN | agonist GABA site | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 54130.51 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_448071 | ||
| Residue: | 473 | ||
| Sequence: |
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| BDBM50214662 | |||
| n/a | |||
| Name | BDBM50214662 | ||
| Synonyms: | 1-(2,6-dichloro-4-trifluoromethylphenyl)-4-ethyl-5-methyl-1H-1,2,3-triazole | CHEMBL392035 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C12H10Cl2F3N3 | ||
| Mol. Mass. | 324.129 | ||
| SMILES | CCc1nnn(c1C)-c1c(Cl)cc(cc1Cl)C(F)(F)F |(2.91,.76,;3.08,2.29,;1.83,3.2,;1.84,4.74,;.37,5.22,;-.53,3.97,;.37,2.73,;-.11,1.26,;-2.07,3.98,;-2.83,2.64,;-2.06,1.31,;-4.37,2.64,;-5.14,3.98,;-4.37,5.31,;-2.83,5.31,;-2.06,6.64,;-6.68,3.98,;-8.24,3.91,;-6.72,5.52,;-6.63,2.44,)| | ||
| Structure | 
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