| Reaction Details |
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 | Report a problem with these data |
| Target | Delta-type opioid receptor |
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| Ligand | BDBM50214842 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_437131 (CHEMBL906528) |
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| Ki | >10000±n/a nM |
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| Citation |  Vergelli, C; Giovannoni, MP; Pieretti, S; Di Giannuario, A; Dal Piaz, V; Biagini, P; Biancalani, C; Graziano, A; Cesari, N 4-Amino-5-vinyl-3(2H)-pyridazinones and analogues as potent antinociceptive agents: Synthesis, SARs, and preliminary studies on the mechanism of action. Bioorg Med Chem15:5563-75 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Delta-type opioid receptor |
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| Name: | Delta-type opioid receptor |
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| Synonyms: | D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 40382.98 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor. |
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| Residue: | 372 |
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| Sequence: | MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVC
AVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELL
CKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVG
VPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRL
RSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAAL
HLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTAC
TPSDGPGGGAAA
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| BDBM50214842 |
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| n/a |
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| Name | BDBM50214842 |
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| Synonyms: | 4-amino-2-butyl-6-phenyl-5-vinylpyridazin-3(2H)-one | CHEMBL227079 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H19N3O |
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| Mol. Mass. | 269.3416 |
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| SMILES | CCCCn1nc(-c2ccccc2)c(C=C)c(N)c1=O |
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| Structure | 
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