| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 4 |
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| Ligand | BDBM50215833 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_447747 (CHEMBL895641) |
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| Ki | 7.9±n/a nM |
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| Citation |  Poitout, L; Brault, V; Sackur, C; Bernetière, S; Camara, J; Plas, P; Roubert, P Identification of a novel series of benzimidazoles as potent and selective antagonists of the human melanocortin-4 receptor. Bioorg Med Chem Lett17:4464-70 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 4 |
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| Name: | Melanocortin receptor 4 |
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| Synonyms: | MC4-R | MC4R | MC4R_HUMAN | Melanocortin MC4 | Melanocortin receptor 4 (MC-4) | Melanocortin receptor 4 (MC4-R) | Melanocortin receptor 4 (MC4R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36949.50 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P32245 |
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| Residue: | 332 |
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| Sequence: | MVNSTHRGMHTSLHLWNRSSYRLHSNASESLGKGYSDGGCYEQLFVSPEVFVTLGVISLL
ENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVN
IDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVS
GILFIIYSDSSAVIICLITMFFTMLALMASLYVHMFLMARLHIKRIAVLPGTGAIRQGAN
MKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCNSIIDPL
IYALRSQELRKTFKEIICCYPLGGLCDLSSRY
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| BDBM50215833 |
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| n/a |
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| Name | BDBM50215833 |
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| Synonyms: | 2-(4-acetylphenylamino)-3-(3-(diethylamino)propyl)-N,N-diisopentyl-3H-benzo[d]imidazole-5-carboxamide | CHEMBL394167 |
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| Type | Small organic molecule |
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| Emp. Form. | C33H49N5O2 |
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| Mol. Mass. | 547.7745 |
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| SMILES | CCN(CC)CCCn1c(Nc2ccc(cc2)C(C)=O)nc2ccc(cc12)C(=O)N(CCC(C)C)CCC(C)C |
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| Structure | 
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