| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melanocyte-stimulating hormone receptor |
|---|
| Ligand | BDBM50217647 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_448689 (CHEMBL896689) |
|---|
| Ki | 1300±n/a nM |
|---|
| Citation |  Mutulis, F; Kreicberga, J; Yahorava, S; Mutule, I; Borisova-Jan, L; Yahorau, A; Muceniece, R; Azena, S; Veiksina, S; Petrovska, R; Wikberg, JE Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core. Bioorg Med Chem15:5787-810 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melanocyte-stimulating hormone receptor |
|---|
| Name: | Melanocyte-stimulating hormone receptor |
|---|
| Synonyms: | MC1-R | MSHR_MOUSE | Mc1r | Melanocortin receptor 1 | Melanocyte-stimulating hormone receptor | Msh-r |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 35238.60 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | ChEMBL_1498846 |
|---|
| Residue: | 315 |
|---|
| Sequence: | MSTQEPQKSLLGSLNSNATSHLGLATNQSEPWCLYVSIPDGLFLSLGLVSLVENVLVVIA
ITKNRNLHSPMYYFICCLALSDLMVSVSIVLETTIILLLEAGILVARVALVQQLDNLIDV
LICGSMVSSLCFLGIIAIDRYISIFYALRYHSIVTLPRARRAVVGIWMVSIVSSTLFITY
YKHTAVLLCLVTFFLAMLALMAILYAHMFTRACQHAQGIAQLHKRRRSIRQGFCLKGAAT
LTILLGIFFLCWGPFFLHLLLIVLCPQHPTCSCIFKNFNLFLLLIVLSSTVDPLIYAFRS
QELRMTLKEVLLCSW
|
|
|
|---|
| BDBM50217647 |
|---|
| n/a |
|---|
| Name | BDBM50217647 |
|---|
| Synonyms: | CHEMBL238154 | N-(4-((4-amino-3-methylcyclohexyl)methyl)-2-methylcyclohexyl)-N-benzyl-4-(1H-indol-3-yl)butanamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C34H47N3O |
|---|
| Mol. Mass. | 513.7565 |
|---|
| SMILES | CC1CC(CC2CCC(C(C)C2)N(Cc2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CCC1N |w:8.12,5.4,3.3,9.9,36.41,1.0| |
|---|
| Structure | 
|
|---|
Search and Browse
