Reaction Details | |||
---|---|---|---|
Report a problem with these data | |||
Target | Melanocortin receptor 5 | ||
Ligand | BDBM50217788 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_448695 (CHEMBL897841) | ||
Ki | 11000±n/a nM | ||
Citation | Mutulis, F; Kreicberga, J; Yahorava, S; Mutule, I; Borisova-Jan, L; Yahorau, A; Muceniece, R; Azena, S; Veiksina, S; Petrovska, R; Wikberg, JE Design and synthesis of a library of tertiary amides: evaluation as mimetics of the melanocortins' active core. Bioorg Med Chem15:5787-810 (2007) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Melanocortin receptor 5 | |||
Name: | Melanocortin receptor 5 | ||
Synonyms: | MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) | ||
Type: | Enzyme | ||
Mol. Mass.: | 36612.92 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P33032 | ||
Residue: | 325 | ||
Sequence: |
| ||
BDBM50217788 | |||
n/a | |||
Name | BDBM50217788 | ||
Synonyms: | (Z)-N-((4-(aminomethyl)cyclohexyl)methyl)-N-(2-chloro-3-phenylallyl)-4-(1H-indol-3-yl)butanamide | CHEMBL238368 | ||
Type | Small organic molecule | ||
Emp. Form. | C29H36ClN3O | ||
Mol. Mass. | 478.069 | ||
SMILES | NCC1CCC(CN(C\C(Cl)=C\c2ccccc2)C(=O)CCCc2c[nH]c3ccccc23)CC1 |(12.03,-2.53,;12.05,-4.06,;10.73,-4.84,;10.75,-6.37,;9.43,-7.16,;8.08,-6.41,;6.75,-7.19,;6.77,-8.73,;5.41,-9.62,;3.96,-8.88,;3.95,-7.24,;2.6,-9.77,;1.15,-9.03,;1.07,-7.41,;-.38,-6.67,;-1.74,-7.56,;-1.65,-9.19,;-.2,-9.92,;8.07,-9.53,;8.04,-11.05,;9.42,-8.79,;10.74,-9.59,;12.09,-8.85,;13.07,-9.11,;13.73,-10.51,;15.25,-10.32,;15.54,-8.8,;16.85,-8.01,;16.82,-6.48,;15.47,-5.74,;14.16,-6.54,;14.2,-8.06,;8.06,-4.87,;9.39,-4.08,)| | ||
Structure |