| Reaction Details |
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 | Report a problem with these data |
| Target | Serine/threonine-protein kinase pim-1 |
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| Ligand | BDBM26659 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_459174 (CHEMBL926333) |
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| IC50 | 4571±n/a nM |
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| Citation |  Holder, S; Lilly, M; Brown, ML Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase. Bioorg Med Chem15:6463-73 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serine/threonine-protein kinase pim-1 |
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| Name: | Serine/threonine-protein kinase pim-1 |
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| Synonyms: | PIM-1 Kinase | PIM1 | PIM1_HUMAN | Proto-oncogene serine/threonine-protein kinase Pim-1 | Serine/threonine-protein kinase (PIM1) | Serine/threonine-protein kinase PIM | Serine/threonine-protein kinase PIM1 | Serine/threonine-protein kinase pim-1 (PIM1) |
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| Type: | Protein |
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| Mol. Mass.: | 35681.82 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P11309 |
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| Residue: | 313 |
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| Sequence: | MLLSKINSLAHLRAAPCNDLHATKLAPGKEKEPLESQYQVGPLLGSGGFGSVYSGIRVSD
NLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFERPDSFVLIL
ERPEPVQDLFDFITERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRG
ELKLIDFGSGALLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDI
PFEHDEEIIRGQVFFRQRVSSECQHLIRWCLALRPSDRPTFEEIQNHPWMQDVLLPQETA
EIHLHSLSPGPSK
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| BDBM26659 |
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| n/a |
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| Name | BDBM26659 |
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| Synonyms: | 7,3-dihydroxyflavone | 7-hydroxy-2-(3-hydroxyphenyl)-4H-chromen-4-one |
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| Type | Flavonoid |
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| Emp. Form. | C15H10O4 |
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| Mol. Mass. | 254.2375 |
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| SMILES | Oc1cccc(c1)-c1cc(=O)c2ccc(O)cc2o1 |
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| Structure | 
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