| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 4 |
|---|
| Ligand | BDBM50174527 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_445954 (CHEMBL896247) |
|---|
| EC50 | 1100000±n/a nM |
|---|
| Citation |  Selvam, C; Goudet, C; Oueslati, N; Pin, JP; Acher, FC L-(+)-2-Amino-4-thiophosphonobutyric acid (L-thioAP4), a new potent agonist of group III metabotropic glutamate receptors: increased distal acidity affords enhanced potency. J Med Chem50:4656-64 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 4 |
|---|
| Name: | Metabotropic glutamate receptor 4 |
|---|
| Synonyms: | GRM4_RAT | Gprc1d | Grm4 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 4 (mGlu4) | Mglur4 | mGlu4 | metabotropic glutamate 4 | metabotropic glutamate 4a |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 101849.79 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P31423 |
|---|
| Residue: | 912 |
|---|
| Sequence: | MSGKGGWAWWWARLPLCLLLSLYAPWVPSSLGKPKGHPHMNSIRIDGDITLGGLFPVHGR
GSEGKACGELKKEKGIHRLEAMLFALDRINNDPDLLPNITLGARILDTCSRDTHALEQSL
TFVQALIEKDGTEVRCGSGGPPIITKPERVVGVIGASGSSVSIMVANILRLFKIPQISYA
STAPDLSDNSRYDFFSRVVPSDTYQAQAMVDIVRALKWNYVSTLASEGSYGESGVEAFIQ
KSRENGGVCIAQSVKIPREPKTGEFDKIIKRLLETSNARGIIIFANEDDIRRVLEAARRA
NQTGHFFWMGSDSWGSKSAPVLRLEEVAEGAVTILPKRMSVRGFDRYFSSRTLDNNRRNI
WFAEFWEDNFHCKLSRHALKKGSHIKKCTNRERIGQDSAYEQEGKVQFVIDAVYAMGHAL
HAMHRDLCPGRVGLCPRMDPVDGTQLLKYIRNVNFSGIAGNPVTFNENGDAPGRYDIYQY
QLRNGSAEYKVIGSWTDHLHLRIERMQWPGSGQQLPRSICSLPCQPGERKKTVKGMACCW
HCEPCTGYQYQVDRYTCKTCPYDMRPTENRTSCQPIPIVKLEWDSPWAVLPLFLAVVGIA
ATLFVVVTFVRYNDTPIVKASGRELSYVLLAGIFLCYATTFLMIAEPDLGTCSLRRIFLG
LGMSISYAALLTKTNRIYRIFEQGKRSVSAPRFISPASQLAITFILISLQLLGICVWFVV
DPSHSVVDFQDQRTLDPRFARGVLKCDISDLSLICLLGYSMLLMVTCTVYAIKTRGVPET
FNEAKPIGFTMYTTCIVWLAFIPIFFGTSQSADKLYIQTTTLTVSVSLSASVSLGMLYMP
KVYIILFHPEQNVPKRKRSLKAVVTAATMSNKFTQKGNFRPNGEAKSELCENLETPALAT
KQTYVTYTNHAI
|
|
|
|---|
| BDBM50174527 |
|---|
| n/a |
|---|
| Name | BDBM50174527 |
|---|
| Synonyms: | (S)-2-Amino-4-(hydroxy-methyl-phosphinoyl)-butyric acid; hydrochloride | CHEMBL145114 | CHEMBL535153 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C5H12NO4P |
|---|
| Mol. Mass. | 181.1268 |
|---|
| SMILES | CP(O)(=O)CC[C@H](N)C(O)=O |
|---|
| Structure | 
|
|---|
Search and Browse
