| Reaction Details |
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 | Report a problem with these data |
| Target | D(2) dopamine receptor |
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| Ligand | BDBM50012961 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_457316 (CHEMBL941849) |
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| Ki | 4.2±n/a nM |
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| Citation |  Stark, D; Piel, M; Hübner, H; Gmeiner, P; Gründer, G; Rösch, F In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D(2)-like dopamine receptors. Bioorg Med Chem15:6819-29 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(2) dopamine receptor |
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| Name: | D(2) dopamine receptor |
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| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
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| Type: | Cell-surface receptors |
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| Mol. Mass.: | 50647.10 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14416 |
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| Residue: | 443 |
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| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
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| BDBM50012961 |
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| n/a |
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| Name | BDBM50012961 |
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| Synonyms: | (-)-(S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide | (S)-N-((1-ethylpyrrolidin-2-yl)methyl)-2-hydroxy-3-iodo-6-methoxybenzamide | CHEMBL267723 | N-((S)-1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide (IBZM) | N-(1-Ethyl-pyrrolidin-2-ylmethyl)-2-hydroxy-3-iodo-6-methoxy-benzamide( (S)-(-)IBZM) |
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| Type | Small organic molecule |
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| Emp. Form. | C15H21IN2O3 |
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| Mol. Mass. | 404.2433 |
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| SMILES | CCN1CCC[C@H]1CNC(=O)c1c(O)c(I)ccc1OC |
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| Structure | 
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