| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-2 adrenergic receptor |
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| Ligand | BDBM50224026 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_458265 (CHEMBL924511) |
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| EC50 | >10000±n/a nM |
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| Citation |  Stevens, FC; Bloomquist, WE; Borel, AG; Cohen, ML; Droste, CA; Heiman, ML; Kriauciunas, A; Sall, DJ; Tinsley, FC; Jesudason, CD Potent oxindole based human beta3 adrenergic receptor agonists. Bioorg Med Chem Lett17:6270-3 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Beta-2 adrenergic receptor |
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| Name: | Beta-2 adrenergic receptor |
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| Synonyms: | ADRB2 | ADRB2R | ADRB2_HUMAN | B2AR | Beta-2 adrenoceptor | Beta-2 adrenoreceptor |
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| Type: | n/a |
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| Mol. Mass.: | 46461.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P07550 |
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| Residue: | 413 |
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| Sequence: | MGQPGNGSAFLLAPNGSHAPDHDVTQERDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
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| BDBM50224026 |
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| n/a |
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| Name | BDBM50224026 |
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| Synonyms: | (S)-6-(4-(2-(2-hydroxy-3-(2-oxoindolin-4-yloxy)propylamino)-2-methylpropyl)phenoxy)nicotinamide | CHEMBL251167 |
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| Type | Small organic molecule |
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| Emp. Form. | C27H30N4O5 |
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| Mol. Mass. | 490.5509 |
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| SMILES | CC(C)(Cc1ccc(Oc2ccc(cn2)C(N)=O)cc1)NC[C@H](O)COc1cccc2NC(=O)Cc12 |
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| Structure | 
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