| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Ligand | BDBM33822 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_452413 (CHEMBL902649) |
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| Kd | >3700000±n/a nM |
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| Citation |  Stebbins, JL; Zhang, Z; Chen, J; Wu, B; Emdadi, A; Williams, ME; Cashman, J; Pellecchia, M Nuclear magnetic resonance fragment-based identification of novel FKBP12 inhibitors. J Med Chem50:6607-17 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Name: | Peptidyl-prolyl cis-trans isomerase FKBP1A |
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| Synonyms: | 12 kDa FK506-binding protein | 12 kDa FKBP | FK506-binding protein 1A | FK506-binding protein 1A (FKBP12) | FKB1A_HUMAN | FKBP-12 | FKBP-1A | FKBP1 | FKBP12 | FKBP1A | Immunophilin FKBP12 | PPIase | PPIase FKBP1A | Peptidyl-prolyl cis-trans isomerase (FKBP) | Rotamase | RyR1/FKBP12 | mTOR/FKBP12A/FKBP12B |
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| Type: | Isomerase |
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| Mol. Mass.: | 11953.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P62942 |
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| Residue: | 108 |
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| Sequence: | MGVQVETISPGDGRTFPKRGQTCVVHYTGMLEDGKKFDSSRDRNKPFKFMLGKQEVIRGW
EEGVAQMSVGQRAKLTISPDYAYGATGHPGIIPPHATLVFDVELLKLE
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| BDBM33822 |
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| n/a |
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| Name | BDBM33822 |
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| Synonyms: | 2-(2-morpholin-4-yl-2-oxidanylidene-ethyl)sulfanylbenzoic acid | 2-(2-morpholin-4-yl-2-oxoethyl)sulfanylbenzoic acid | 2-[(2-keto-2-morpholino-ethyl)thio]benzoic acid | 2-[[2-(4-morpholinyl)-2-oxoethyl]thio]benzoic acid | 2-{[2-(4-morpholinyl)-2-oxoethyl]thio}benzoic acid | CHEMBL396324 | MLS000862372 | SMR000300822 | cid_1249560 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H15NO4S |
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| Mol. Mass. | 281.328 |
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| SMILES | OC(=O)c1ccccc1SCC(=O)N1CCOCC1 |
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| Structure | 
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