| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A3 |
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| Ligand | BDBM50228372 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_452418 (CHEMBL902654) |
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| Ki | 25.3±n/a nM |
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| Citation |  Morizzo, E; Capelli, F; Lenzi, O; Catarzi, D; Varano, F; Filacchioni, G; Vincenzi, F; Varani, K; Borea, PA; Colotta, V; Moro, S Scouting human A3 adenosine receptor antagonist binding mode using a molecular simplification approach: from triazoloquinoxaline to a pyrimidine skeleton as a key study. J Med Chem50:6596-606 (2007) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A3 |
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| Name: | Adenosine receptor A3 |
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| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36197.32 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P0DMS8 |
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| Residue: | 318 |
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| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
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| BDBM50228372 |
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| n/a |
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| Name | BDBM50228372 |
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| Synonyms: | 2-acetylaminoquinazoline-4-carboxyanilide | CHEMBL239193 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H14N4O2 |
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| Mol. Mass. | 306.3187 |
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| SMILES | CC(=O)Nc1nc(C(=O)Nc2ccccc2)c2ccccc2n1 |
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| Structure | 
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