| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50233101 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_462282 (CHEMBL946045) |
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| Ki | 1730±n/a nM |
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| Citation |  Kalla, RV; Elzein, E; Perry, T; Li, X; Gimbel, A; Yang, M; Zeng, D; Zablocki, J Selective, high affinity A(2B) adenosine receptor antagonists: N-1 monosubstituted 8-(pyrazol-4-yl)xanthines. Bioorg Med Chem Lett18:1397-401 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50233101 |
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| n/a |
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| Name | BDBM50233101 |
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| Synonyms: | 8-(1-(3-fluorobenzyl)-1H-pyrazol-4-yl)-1-propyl-1H-purine-2,6(3H,7H)-dione | CHEMBL404131 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17FN6O2 |
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| Mol. Mass. | 368.365 |
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| SMILES | CCCn1c(=O)[nH]c2nc([nH]c2c1=O)-c1cnn(Cc2cccc(F)c2)c1 |
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| Structure | 
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