| Reaction Details |
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 | Report a problem with these data |
| Target | Deoxyribonuclease-1 |
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| Ligand | BDBM50164888 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_509269 (CHEMBL996013) |
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| IC50 | >400000±n/a nM |
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| Citation |  Suzuki, K; Yahara, S; Maehata, K; Uyeda, M Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. J Nat Prod64:204-7 (2001) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Deoxyribonuclease-1 |
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| Name: | Deoxyribonuclease-1 |
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| Synonyms: | DNAS1_BOVIN | DNASE1 | DNL1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 31341.11 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_1297301 |
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| Residue: | 282 |
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| Sequence: | MRGTRLMGLLLALAGLLQLGLSLKIAAFNIRTFGETKMSNATLASYIVRIVRRYDIVLIQ
EVRDSHLVAVGKLLDYLNQDDPNTYHYVVSEPLGRNSYKERYLFLFRPNKVSVLDTYQYD
DGCESCGNDSFSREPAVVKFSSHSTKVKEFAIVALHSAPSDAVAEINSLYDVYLDVQQKW
HLNDVMLMGDFNADCSYVTSSQWSSIRLRTSSTFQWLIPDSADTTATSTNCAYDRIVVAG
SLLQSSVVPGSAAPFDFQAAYGLSNEMALAISDHYPVEVTLT
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| BDBM50164888 |
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| n/a |
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| Name | BDBM50164888 |
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| Synonyms: | 6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-3H-benzofuran-2-one | CHEMBL195416 | isoaurostatin |
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| Type | Small organic molecule |
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| Emp. Form. | C15H10O4 |
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| Mol. Mass. | 254.2375 |
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| SMILES | Oc1ccc(\C=C2\C(=O)Oc3cc(O)ccc23)cc1 |
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| Structure | 
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