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TargetType II restriction enzyme ScaI
LigandBDBM50164888
Substrate/Competitorn/a
Meas. Tech.ChEMBL_504717 (CHEMBL990277)
IC50>400000±n/a nM
Citation Suzuki, KYahara, SMaehata, KUyeda, M Isoaurostatin, a novel topoisomerase inhibitor produced by Thermomonospora alba. J Nat Prod64:204-7 (2001) [PubMed]
More Info.:Get all data from this article,  Assay Method
 
Type II restriction enzyme ScaI
Name:Type II restriction enzyme ScaI
Synonyms:T2S1_STRCS | Type-2 restriction enzyme ScaI | scaIR
Type:PROTEIN
Mol. Mass.:25466.25
Organism:Streptomyces caespitosus
Description:ChEMBL_504717
Residue:227
Sequence:
MINDQLPRWVREARVGTRTGGPAMRPKTSDSPYFGWDSEDWPEVTRQLLSEQPLSGDTLV
DAVLASWESIFESRLGSGFHIGTQIRPTPQVMGFLLHALIPLELANGDPSWRADLNSSEK
DLVYQPDHKYSIEMKTSSHKDQIFGNRSFGVENPGKGKKAKDGYYVAVNFEKWSDAPGRL
PRIRTIRYGWLDHTDWVAQKSQTGQQSSLPAVVSNTQLLAIHTGGQR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM50164888
n/a
NameBDBM50164888
Synonyms:6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-3H-benzofuran-2-one | CHEMBL195416 | isoaurostatin
TypeSmall organic molecule
Emp. Form.C15H10O4
Mol. Mass.254.2375
SMILESOc1ccc(\C=C2\C(=O)Oc3cc(O)ccc23)cc1
Structure
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