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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Proto-oncogene tyrosine-protein kinase Src | ||
| Ligand | BDBM50259898 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_526200 (CHEMBL974769) | ||
| IC50 | 3900±n/a nM | ||
| Citation |  Puder, C; Wagner, K; Vettermann, R; Hauptmann, R; Potterat, O Terphenylquinone inhibitors of the src protein tyrosine kinase from Stilbella sp. J Nat Prod68:323-6 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Proto-oncogene tyrosine-protein kinase Src | |||
| Name: | Proto-oncogene tyrosine-protein kinase Src | ||
| Synonyms: | Calmodulin/Proto-oncogene tyrosine-protein kinase Src | Protein cereblon/Tyrosine-protein kinase SRC | Proto-oncogene c-Src | Proto-oncogene tyrosine-protein kinase Src (c-Src) | SRC | SRC1 | SRC_HUMAN | Tyrosine-protein kinase Src (SRC) | V-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian) | c-Src | p60-Src | pp60c-src | ||
| Type: | Protein | ||
| Mol. Mass.: | 59838.60 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P12931 | ||
| Residue: | 536 | ||
| Sequence: |
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| BDBM50259898 | |||
| n/a | |||
| Name | BDBM50259898 | ||
| Synonyms: | 2,5-Dihydroxy-3-phenyl-6-(3,4,5-trihydroxyphenyl)-1,4-benzoquinone | CHEMBL470336 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H12O7 | ||
| Mol. Mass. | 340.2837 | ||
| SMILES | Oc1cc(cc(O)c1O)C1C(=O)C(=O)C(C(=O)C1=O)c1ccccc1 |(23.7,-16.67,;22.86,-15.37,;21.33,-15.44,;20.5,-14.15,;21.2,-12.78,;22.73,-12.7,;23.43,-11.33,;23.57,-14,;25.11,-13.93,;18.96,-14.22,;18.13,-12.92,;18.83,-11.55,;16.59,-13,;15.75,-11.7,;15.89,-14.36,;16.72,-15.66,;16.02,-17.03,;18.26,-15.59,;19.09,-16.88,;14.35,-14.44,;13.51,-13.15,;11.98,-13.22,;11.27,-14.6,;12.1,-15.89,;13.64,-15.82,)| | ||
| Structure | 
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