| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Na(+)/H(+) antiporter NhaA |
|---|
| Ligand | BDBM50010751 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_533986 (CHEMBL994875) |
|---|
| IC50 | 1700±n/a nM |
|---|
| Citation |  Landau, M; Herz, K; Padan, E; Ben-Tal, N Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications. J Biol Chem282:37854-63 (2007) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Na(+)/H(+) antiporter NhaA |
|---|
| Name: | Na(+)/H(+) antiporter NhaA |
|---|
| Synonyms: | NHAA_ECOLI | ant | nhaA |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41365.27 |
|---|
| Organism: | Escherichia coli (strain K12) |
|---|
| Description: | ChEMBL_533985 |
|---|
| Residue: | 388 |
|---|
| Sequence: | MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLETPVQLRVGSLEINKNML
LWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAIGGMIVPALLYLAFNYADP
ITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALAIIDDLGAIIIIALFYTNDLS
MASLGVAAVAIAVLAVLNLCGARRTGVYILVGVVLWTAVLKSGVHATLAGVIVGFFIPLK
EKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSLQGVTLDGLTSILPLGIIAGLLIGK
PLGISLFCWLALRLKLAHLPEGTTYQQIMVVGILCGIGFTMSIFIASLAFGSVDPELINW
AKLGILVGSISSAVIGYSWLRVRLRPSV
|
|
|
|---|
| BDBM50010751 |
|---|
| n/a |
|---|
| Name | BDBM50010751 |
|---|
| Synonyms: | 1H,3H-Perimidin-2-ylideneamine | 2-aminoperimidine | CHEMBL311074 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C11H9N3 |
|---|
| Mol. Mass. | 183.2093 |
|---|
| SMILES | Nc1nc2cccc3cccc([nH]1)c23 |
|---|
| Structure | 
|
|---|
Search and Browse
