Reaction Details |
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Target | Sigma non-opioid intracellular receptor 1 |
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Ligand | BDBM50265436 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_497294 (CHEMBL995856) |
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Ki | 0.380000±n/a nM |
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Citation | Mercer, SL; Shaikh, J; Traynor, JR; Matsumoto, RR; Coop, A Nitrile analogs of meperidine as high affinity and selective sigma-1 receptor ligands. Eur J Med Chem43:1304-8 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Sigma non-opioid intracellular receptor 1 |
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Name: | Sigma non-opioid intracellular receptor 1 |
Synonyms: | Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 25266.54 |
Organism: | RAT |
Description: | Q9R0C9 |
Residue: | 223 |
Sequence: | MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRY
WAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
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BDBM50265436 |
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n/a |
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Name | BDBM50265436 |
Synonyms: | 1-Phenylpropyl-4-phenylpiperidine-4-carbonitrile | CHEMBL502461 |
Type | Small organic molecule |
Emp. Form. | C21H24N2 |
Mol. Mass. | 304.4287 |
SMILES | N#CC1(CCN(CCCc2ccccc2)CC1)c1ccccc1 |
Structure |
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