| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50260410 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_530192 (CHEMBL973055) |
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| IC50 | 2690±n/a nM |
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| Citation |  Ettaoussi, M; Péres, B; Klupsch, F; Delagrange, P; Boutin, JA; Renard, P; Caignard, DH; Chavatte, P; Berthelot, P; Lesieur, D; Yous, S Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3. Bioorg Med Chem16:4954-62 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50260410 |
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| n/a |
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| Name | BDBM50260410 |
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| Synonyms: | CHEMBL493424 | N-(2-(5-Methoxycarbonylamino-benzo[b]furan-3-yl)ethyl)vinylacetamide | methyl 3-(2-but-3-enamidoethyl)benzofuran-5-ylcarbamate |
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| Type | Small organic molecule |
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| Emp. Form. | C16H18N2O4 |
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| Mol. Mass. | 302.3251 |
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| SMILES | COC(=O)Nc1ccc2occ(CCNC(=O)CC=C)c2c1 |
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| Structure | 
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