| Reaction Details |
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 | Report a problem with these data |
| Target | Glutathione hydrolase 1 proenzyme |
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| Ligand | BDBM50248625 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_543160 (CHEMBL1014320) |
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| IC50 | 22000±n/a nM |
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| Citation |  Sadanandam, YS; Shetty, MM; Rao, AB; Rambabu, Y 10H-Phenothiazines: a new class of enzyme inhibitors for inflammatory diseases. Eur J Med Chem44:197-202 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutathione hydrolase 1 proenzyme |
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| Name: | Glutathione hydrolase 1 proenzyme |
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| Synonyms: | GGT | GGT1 | GGT1_HUMAN | Gamma-glutamyltranspeptidase 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61413.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_543160 |
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| Residue: | 569 |
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| Sequence: | MKKKLVVLGLLAVVLVLVIVGLCLWLPSASKEPDNHVYTRAAVAADAKQCSKIGRDALRD
GGSAVDAAIAALLCVGLMNAHSMGIGGGLFLTIYNSTTRKAEVINAREVAPRLAFATMFN
SSEQSQKGGLSVAVPGEIRGYELAHQRHGRLPWARLFQPSIQLARQGFPVGKGLAAALEN
KRTVIEQQPVLCEVFCRDRKVLREGERLTLPQLADTYETLAIEGAQAFYNGSLTAQIVKD
IQAAGGIVTAEDLNNYRAELIEHPLNISLGDVVLYMPSAPLSGPVLALILNILKGYNFSR
ESVESPEQKGLTYHRIVEAFRFAYAKRTLLGDPKFVDVTEVVRNMTSEFFAAQLRAQISD
DTTHPISYYKPEFYTPDDGGTAHLSVVAEDGSAVSATSTINLYFGSKVRSPVSGILFNNE
MDDFSSPSITNEFGVPPSPANFIQPGKQPLSSMCPTIMVGQDGQVRMVVGAAGGTQITTA
TALAIIYNLWFGYDVKRAVEEPRLHNQLLPNVTTVERNIDQAVTAALETRHHHTQIASTF
IAVVQAIVRTAGGWAAASDSRKGGEPAGY
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| BDBM50248625 |
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| n/a |
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| Name | BDBM50248625 |
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| Synonyms: | 2-(2-Methylphenyl)-N,N',4-trimethyl-2,10-dihydro-1Hphenothiazine-1,3-dicarboxamide | CHEMBL464297 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H25N3O2S |
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| Mol. Mass. | 419.539 |
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| SMILES | CNC(=O)C1C(C(C(=O)NC)C2=Nc3ccccc3SC2=C1C)c1ccccc1C |c:22,t:11| |
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| Structure | 
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