| Reaction Details |
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 | Report a problem with these data |
| Target | Glucagon-like peptide 1 receptor |
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| Ligand | BDBM50241203 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_533246 (CHEMBL972348) |
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| IC50 | 0.660000±n/a nM |
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| Citation |  Miranda, LP; Winters, KA; Gegg, CV; Patel, A; Aral, J; Long, J; Zhang, J; Diamond, S; Guido, M; Stanislaus, S; Ma, M; Li, H; Rose, MJ; Poppe, L; Véniant, MM Design and synthesis of conformationally constrained glucagon-like peptide-1 derivatives with increased plasma stability and prolonged in vivo activity. J Med Chem51:2758-65 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glucagon-like peptide 1 receptor |
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| Name: | Glucagon-like peptide 1 receptor |
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| Synonyms: | GLP-1 receptor | GLP-1-R | GLP-1R | GLP1R | GLP1R_HUMAN | Glucagon-like peptide 1 receptor | Glucagon-like peptide 1 receptor (GLP-1) |
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| Type: | Enzyme |
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| Mol. Mass.: | 53035.78 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P43220 |
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| Residue: | 463 |
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| Sequence: | MAGAPGPLRLALLLLGMVGRAGPRPQGATVSLWETVQKWREYRRQCQRSLTEDPPPATDL
FCNRTFDEYACWPDGEPGSFVNVSCPWYLPWASSVPQGHVYRFCTAEGLWLQKDNSSLPW
RDLSECEESKRGERSSPEEQLLFLYIIYTVGYALSFSALVIASAILLGFRHLHCTRNYIH
LNLFASFILRALSVFIKDAALKWMYSTAAQQHQWDGLLSYQDSLSCRLVFLLMQYCVAAN
YYWLLVEGVYLYTLLAFSVLSEQWIFRLYVSIGWGVPLLFVVPWGIVKYLYEDEGCWTRN
SNMNYWLIIRLPILFAIGVNFLIFVRVICIVVSKLKANLMCKTDIKCRLAKSTLTLIPLL
GTHEVIFAFVMDEHARGTLRFIKLFTELSFTSFQGLMVAILYCFVNNEVQLEFRKSWERW
RLEHLHIQRDSSMKPLKCPTSSLSSGATAGSSMYTATCQASCS
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| BDBM50241203 |
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| n/a |
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| Name | BDBM50241203 |
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| Synonyms: | CHEMBL414357 | HGEGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGSPPPS-NH2 | exenatide | exendin-4 |
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| Type | Small organic molecule |
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| Emp. Form. | C184H282N50O60S |
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| Mol. Mass. | 4186.572 |
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| SMILES | n/a |
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| Structure | 
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