| Reaction Details |
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 | Report a problem with these data |
| Target | Arachidonate 5-lipoxygenase-activating protein |
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| Ligand | BDBM26197 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_553560 (CHEMBL958743) |
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| IC50 | 44000±n/a nM |
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| Citation |  Friesen, RW; Mancini, JA Microsomal prostaglandin E2 synthase-1 (mPGES-1): a novel anti-inflammatory therapeutic target. J Med Chem51:4059-67 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Arachidonate 5-lipoxygenase-activating protein |
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| Name: | Arachidonate 5-lipoxygenase-activating protein |
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| Synonyms: | 5-lipoxygenase activating protein | 5-lipoxygenase-activating protein (FLAP) | 5-lipoxygenase/FLAP | AL5AP_HUMAN | ALOX5AP | FLAP | MK-886-binding protein |
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| Type: | Enzyme |
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| Mol. Mass.: | 18159.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P20292 |
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| Residue: | 161 |
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| Sequence: | MDQETVGNVVLLAIVTLISVVQNGFFAHKVEHESRTQNGRSFQRTGTLAFERVYTANQNC
VDAYPTFLAVLWSAGLLCSQVPAAFAGLMYLFVRQKYFVGYLGERTQSTPGYIFGKRIIL
FLFLMSVAGIFNYYLIFFFGSDFENYIKTISTTISPLLLIP
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| BDBM26197 |
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| n/a |
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| Name | BDBM26197 |
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| Synonyms: | CHEMBL112 | N-(4-hydroxyphenyl)acetamide | Norco | Paracetamol | US9333197, Acetaminophen | acetaminophen | phenol derivative, 11 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H9NO2 |
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| Mol. Mass. | 151.1626 |
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| SMILES | CC(=O)Nc1ccc(O)cc1 |
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| Structure | 
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