| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamine synthetase |
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| Ligand | BDBM50260535 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_555756 (CHEMBL959113) |
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| Ki | 40000±n/a nM |
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| Citation |  Nordqvist, A; Nilsson, MT; Röttger, S; Odell, LR; Krajewski, WW; Evalena Andersson, C; Larhed, M; Mowbray, SL; Karlén, A Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery. Bioorg Med Chem16:5501-13 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamine synthetase |
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| Name: | Glutamine synthetase |
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| Synonyms: | GLN1B_SALTY | glnA |
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| Type: | PROTEIN |
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| Mol. Mass.: | 51775.05 |
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| Organism: | Salmonella typhimurium |
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| Description: | ChEMBL_555756 |
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| Residue: | 469 |
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| Sequence: | MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFFEEGKMFDGSSIGGWKG
INESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYDRDPRSIAKRAEDYLRATG
IADTVLFGPEPEFFLFDDIRFGASISGSHVAIDDIEGAWNSSTKYEGGNKGHRPGVKGGY
FPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAGQNEVATRFNTMTKKADEIQIYK
YVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLAKNGTNLFSGDKYAGLSEQALYYIG
GVIKHAKAINALANPTTNSYKRLVPGYEAPVMLAYSARNRSASIRIPVVASPKARRIEVR
FPDPAANPYLCFAALLMAGLDGIKNKIHPGEAMDKNLYDLPPEEAKEIPQVAGSLEEALN
ALDLDREFLKAGGVFTDEAIDAYIALRREEDDRVRMTPHPVEFELYYSV
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| BDBM50260535 |
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| n/a |
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| Name | BDBM50260535 |
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| Synonyms: | (2S,5R)-2,6-diamino-5-hydroxyhexanoic acid | (2S,5R)-5-hydroxylysine | CHEMBL457104 | L-normal-5-hydroxylysine | erythro-5-hydroxy-L-lysine |
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| Type | Small organic molecule |
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| Emp. Form. | C6H14N2O3 |
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| Mol. Mass. | 162.187 |
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| SMILES | NC[C@H](O)CC[C@H](N)C(O)=O |r| |
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| Structure | 
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