| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50267387 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_563916 (CHEMBL965019) |
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| Ki | >10000±n/a nM |
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| Citation |  Bedürftig, S; Wünsch, B 1,4-Diazepanes derived from (S)-serine--homopiperazines with improved sigma(1) (sigma) receptor affinity and selectivity. Eur J Med Chem44:519-25 (2009) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein |
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| Type: | Protein |
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| Mol. Mass.: | 25307.17 |
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| Organism: | Cavia porcellus (Guinea pig) |
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| Description: | Q60492 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSK
LIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
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| BDBM50267387 |
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| n/a |
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| Name | BDBM50267387 |
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| Synonyms: | (R)-(1-benzyl-4-(2,2-dimethoxyethyl)piperazin-2-yl)methanol | CHEMBL477037 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H26N2O3 |
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| Mol. Mass. | 294.3892 |
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| SMILES | COC(CN1CCN(Cc2ccccc2)[C@@H](CO)C1)OC |r| |
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| Structure | 
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