| Reaction Details |
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 | Report a problem with these data |
| Target | Aldo-keto reductase family 1 member B1 |
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| Ligand | BDBM50292598 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_492080 (CHEMBL946246) |
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| IC50 | 432±n/a nM |
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| Citation |  Bozdağ-Dündar, O; Verspohl, EJ; Das-Evcimen, N; Kaup, RM; Bauer, K; Sarikaya, M; Evranos, B; Ertan, R Synthesis and biological activity of some new flavonyl-2,4-thiazolidinediones. Bioorg Med Chem16:6747-51 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Aldo-keto reductase family 1 member B1 |
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| Name: | Aldo-keto reductase family 1 member B1 |
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| Synonyms: | ALDR_RAT | Akr1b1 | Akr1b4 | Aldose reductase | Aldr1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 35797.87 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_1512484 |
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| Residue: | 316 |
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| Sequence: | MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQ
EKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDLQLDYLDLYLIHWPTGFKPGP
DYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKP
AVNQIECHPYLTQEKLIEYCHCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAK
YNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA
LMSCAKHKDYPFHAEV
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| BDBM50292598 |
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| n/a |
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| Name | BDBM50292598 |
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| Synonyms: | 5-((4-(4-oxo-4H-chromen-2-yl)phenyl)methylene)thiazolidine-2,4-dione | CHEMBL494695 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H11NO4S |
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| Mol. Mass. | 349.36 |
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| SMILES | O=C1NC(=O)\C(S1)=C\c1ccc(cc1)-c1cc(=O)c2ccccc2o1 |
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| Structure | 
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