| Reaction Details |
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 | Report a problem with these data |
| Target | Neuronal acetylcholine receptor subunit alpha-4 |
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| Ligand | BDBM50212288 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_492116 (CHEMBL947458) |
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| IC50 | 2600±n/a nM |
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| Citation |  Tomizawa, M; Kagabu, S; Ohno, I; Durkin, KA; Casida, JE Potency and selectivity of trifluoroacetylimino and pyrazinoylimino nicotinic insecticides and their fit at a unique binding site niche. J Med Chem51:4213-8 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuronal acetylcholine receptor subunit alpha-4 |
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| Name: | Neuronal acetylcholine receptor subunit alpha-4 |
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| Synonyms: | ACHA4_CHICK | CHRNA4 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 70849.36 |
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| Organism: | Gallus gallus |
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| Description: | ChEMBL_492116 |
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| Residue: | 622 |
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| Sequence: | MGFLVSKGNLLLLLCASIFPAFGHVETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVR
FGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPQEYENVTSIRIPSELIWRPDIVL
YNNADGDFAVTHLTKAHLFYDGRIKWMPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYD
KAKIDLVSMHSHVDQLDYWESGEWVIINAVGNYNSKKYECCTEIYPDITYSFIIRRLPLF
YTINLIIPCLLISCLTVLVFYLPSECGEKITLCISVLLSLTVFLLLITEIIPSTSLVIPL
IGEYLLFTMIFVTLSIIITVFVLNVHHRSPRTHTMPDWVRRVFLDIVPRLLFMKRPSTVK
DNCKKLIESMHKLTNSPRLWSETDMEPNFTTSSSPSPQSNEPSPTSSFCAHLEEPAKPMC
KSPSGQYSMLHPEPPQVTCSSPKPSCHPLSDTQTTSISKGRSLSVQQMYSPNKTEEGSIR
CRSRSIQYCYLQEDSSQTNGHSSASPASQRCHLNEEQPQHKPHQCKCKCRKGEAAGTPTQ
GSKSHSNKGEHLVLMSPALKLAVEGVHYIADHLRAEDADFSVKEDWKYVAMVIDRIFLWM
FIIVCLLGTVGLFLPPWLAGMI
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| BDBM50212288 |
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| n/a |
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| Name | BDBM50212288 |
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| Synonyms: | (2E)-1-[(6-chloropyridin-3-yl)methyl]-N-nitroimidazolidin-2-imine | (E)-imidacloprid | CHEMBL406819 |
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| Type | Small organic molecule |
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| Emp. Form. | C9H10ClN5O2 |
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| Mol. Mass. | 255.661 |
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| SMILES | [O-][N+](=O)NC1=NCCN1Cc1ccc(Cl)nc1 |t:4| |
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| Structure | 
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