Reaction Details |
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Target | Bcl2-associated agonist of cell death |
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Ligand | BDBM50262596 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_489247 (CHEMBL989994) |
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Kd | 1000000±n/a nM |
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Citation | Prakesch, M; Denisov, AY; Naim, M; Gehring, K; Arya, P The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1. Bioorg Med Chem16:7443-9 (2008) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Bcl2-associated agonist of cell death |
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Name: | Bcl2-associated agonist of cell death |
Synonyms: | BAD_MOUSE | Bad | Bbc6 | GST fusion protein of Bcl2 antagonist of cell death | GST-BAD |
Type: | Other Protein Type |
Mol. Mass.: | 22084.58 |
Organism: | Mus musculus (mouse) |
Description: | n/a |
Residue: | 204 |
Sequence: | MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASAT
DRGLGPSLTEDQPGPYLAPGLLGSNIHQQGRAATNSHHGGAGAMETRSRHSSYPAGTEED
EGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGLPRPKSAGTATQMRQS
AGWTRIIQSWWDRNLGKGGSTPSQ
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BDBM50262596 |
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n/a |
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Name | BDBM50262596 |
Synonyms: | 2-((2S,3R,4S)-4-(2-naphthamido)-1-(2-naphthoyl)-3-hydroxy-6-((2-methoxyethoxy)methoxy)-1,2,3,4-tetrahydroquinolin-2-yl)acetic acid | CHEMBL446860 |
Type | Small organic molecule |
Emp. Form. | C37H34N2O8 |
Mol. Mass. | 634.6745 |
SMILES | COCCOCOc1ccc2N([C@@H](CC(O)=O)[C@H](O)[C@@H](NC(=O)c3ccc4ccccc4c3)c2c1)C(=O)c1ccc2ccccc2c1 |r| |
Structure |
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