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TargetBcl2-associated agonist of cell death
LigandBDBM50262596
Substrate/Competitorn/a
Meas. Tech.ChEMBL_489247 (CHEMBL989994)
Kd 1000000±n/a nM
Citation Prakesch, MDenisov, AYNaim, MGehring, KArya, P The discovery of small molecule chemical probes of Bcl-X(L) and Mcl-1. Bioorg Med Chem16:7443-9 (2008) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Bcl2-associated agonist of cell death
Name:Bcl2-associated agonist of cell death
Synonyms:BAD_MOUSE | Bad | Bbc6 | GST fusion protein of Bcl2 antagonist of cell death | GST-BAD
Type:Other Protein Type
Mol. Mass.:22084.58
Organism:Mus musculus (mouse)
Description:n/a
Residue:204
Sequence:
MGTPKQPSLAPAHALGLRKSDPGIRSLGSDAGGRRWRPAAQSMFQIPEFEPSEQEDASAT
DRGLGPSLTEDQPGPYLAPGLLGSNIHQQGRAATNSHHGGAGAMETRSRHSSYPAGTEED
EGMEEELSPFRGRSRSAPPNLWAAQRYGRELRRMSDEFEGSFKGLPRPKSAGTATQMRQS
AGWTRIIQSWWDRNLGKGGSTPSQ
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  Blast E-value cutoff:
BDBM50262596
n/a
NameBDBM50262596
Synonyms:2-((2S,3R,4S)-4-(2-naphthamido)-1-(2-naphthoyl)-3-hydroxy-6-((2-methoxyethoxy)methoxy)-1,2,3,4-tetrahydroquinolin-2-yl)acetic acid | CHEMBL446860
TypeSmall organic molecule
Emp. Form.C37H34N2O8
Mol. Mass.634.6745
SMILESCOCCOCOc1ccc2N([C@@H](CC(O)=O)[C@H](O)[C@@H](NC(=O)c3ccc4ccccc4c3)c2c1)C(=O)c1ccc2ccccc2c1 |r|
Structure
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