| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Oxytocin receptor |
|---|
| Ligand | BDBM50262152 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_513959 (CHEMBL974600) |
|---|
| Ki | 50±n/a nM |
|---|
| Citation |  Brown, A; Brown, L; Ellis, D; Puhalo, N; Smith, CR; Wallace, O; Watson, L Design and optimization of potent, selective antagonists of Oxytocin. Bioorg Med Chem Lett18:4278-81 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Oxytocin receptor |
|---|
| Name: | Oxytocin receptor |
|---|
| Synonyms: | OT-R | OXTR | OXYR_HUMAN | Oxytocin |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 42793.26 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Oxytocin OXTR HEK293::B2R9L7 |
|---|
| Residue: | 389 |
|---|
| Sequence: | MEGALAANWSAEAANASAAPPGAEGNRTAGPPRRNEALARVEVAVLCLILLLALSGNACV
LLALRTTRQKHSRLFFFMKHLSIADLVVAVFQVLPQLLWDITFRFYGPDLLCRLVKYLQV
VGMFASTYLLLLMSLDRCLAICQPLRSLRRRTDRLAVLATWLGCLVASAPQVHIFSLREV
ADGVFDCWAVFIQPWGPKAYITWITLAVYIVPVIVLAACYGLISFKIWQNLRLKTAAAAA
AEAPEGAAAGDGGRVALARVSSVKLISKAKIRTVKMTFIIVLAFIVCWTPFFFVQMWSVW
DANAPKEASAFIIVMLLASLNSCCNPWIYMLFTGHLFHELVQRFLCCSASYLKGRRLGET
SASKKSNSSSFVLSHRSSSQRSCSQPSTA
|
|
|
|---|
| BDBM50262152 |
|---|
| n/a |
|---|
| Name | BDBM50262152 |
|---|
| Synonyms: | (R)-1-(2'-Methyl-biphenyl-4-carbonyl)-5-[1,2,4]oxadiazol-5-yl-pyrrolidin-3-one O-methyl-oxime | CHEMBL467153 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H20N4O3 |
|---|
| Mol. Mass. | 376.4085 |
|---|
| SMILES | CO\N=C1\C[C@@H](N(C1)C(=O)c1ccc(cc1)-c1ccccc1C)c1ncno1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
