| Reaction Details |
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 | Report a problem with these data |
| Target | Melanocortin receptor 5 |
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| Ligand | BDBM50245765 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_513117 (CHEMBL973606) |
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| Ki | 540±n/a nM |
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| Citation |  Marinkovic, D; Tucci, FC; Tran, JA; Fleck, BA; Wen, J; Chen, C Structure-activity relationship studies on a series of piperazinebenzylalcohols and their ketone and amine analogs as melanocortin-4 receptor ligands. Bioorg Med Chem Lett18:4817-22 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melanocortin receptor 5 |
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| Name: | Melanocortin receptor 5 |
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| Synonyms: | MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R) |
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| Type: | Enzyme |
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| Mol. Mass.: | 36612.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P33032 |
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| Residue: | 325 |
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| Sequence: | MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGA
IVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDS
MICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILY
SESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTV
TMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQ
EMRKTFKEIICCRGFRIACSFPRRD
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| BDBM50245765 |
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| n/a |
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| Name | BDBM50245765 |
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| Synonyms: | CHEMBL454916 | N-((R)-3-(2,4-dichlorophenyl)-1-(4-(2-(1-hydroxy-3-methylbutyl)phenyl)piperazin-1-yl)-1-oxopropan-2-yl)-2-(dimethylamino)acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C28H38Cl2N4O3 |
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| Mol. Mass. | 549.532 |
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| SMILES | CC(C)CC(O)c1ccccc1N1CCN(CC1)C(=O)[C@@H](Cc1ccc(Cl)cc1Cl)NC(=O)CN(C)C |r| |
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| Structure | 
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