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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein phosphatase non-receptor type 2 | ||
| Ligand | BDBM50246665 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_557716 (CHEMBL963011) | ||
| IC50 | 450±n/a nM | ||
| Citation |  Zhang, YN; Zhang, W; Hong, D; Shi, L; Shen, Q; Li, JY; Li, J; Hu, LH Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities. Bioorg Med Chem16:8697-705 (2008) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein phosphatase non-receptor type 2 | |||
| Name: | Tyrosine-protein phosphatase non-receptor type 2 | ||
| Synonyms: | PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP) | ||
| Type: | Protein | ||
| Mol. Mass.: | 48481.80 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P17706 | ||
| Residue: | 415 | ||
| Sequence: |
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| BDBM50246665 | |||
| n/a | |||
| Name | BDBM50246665 | ||
| Synonyms: | 2-(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicen-4a-yl)pentanamido)-3-(2-methoxyphenyl)propanoic acid | CHEMBL446573 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C44H67NO5 | ||
| Mol. Mass. | 690.0065 | ||
| SMILES | COc1ccccc1CC(NC(=O)CCCC[C@]12CCC(C)(C)C[C@H]1C1=CC[C@@H]3[C@@]4(C)CC[C@H](O)C(C)(C)[C@@H]4CC[C@@]3(C)[C@]1(C)CC2)C(O)=O |r,t:27| | ||
| Structure | 
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