Reaction Details | |||
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Target | Tyrosine-protein phosphatase non-receptor type 2 | ||
Ligand | BDBM50246666 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_557716 (CHEMBL963011) | ||
IC50 | 520±n/a nM | ||
Citation | Zhang, YN; Zhang, W; Hong, D; Shi, L; Shen, Q; Li, JY; Li, J; Hu, LH Oleanolic acid and its derivatives: new inhibitor of protein tyrosine phosphatase 1B with cellular activities. Bioorg Med Chem16:8697-705 (2008) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
Tyrosine-protein phosphatase non-receptor type 2 | |||
Name: | Tyrosine-protein phosphatase non-receptor type 2 | ||
Synonyms: | PTN2_HUMAN | PTPN2 | PTPT | T-cell protein tyrosine phosphatase (TCPTP) | T-cell protein-tyrosine phosphatase | TC-PTP | TCPTP | Tyrosine-protein phosphatase non-receptor type 2 | Tyrosine-protein phosphatase non-receptor type 2 (TC-PTP) | ||
Type: | Protein | ||
Mol. Mass.: | 48481.80 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P17706 | ||
Residue: | 415 | ||
Sequence: |
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BDBM50246666 | |||
n/a | |||
Name | BDBM50246666 | ||
Synonyms: | 2-(5-((4aR,6aS,6bR,8aR,10S,12aR,12bR,14bR)-10-hydroxy-2,2,6a,6b,9,9,12a-heptamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,12b,13,14b-icosahydropicen-4a-yl)pentanamido)-3-(3-methoxyphenyl)propanoic acid | CHEMBL506260 | ||
Type | Small organic molecule | ||
Emp. Form. | C44H67NO5 | ||
Mol. Mass. | 690.0065 | ||
SMILES | COc1cccc(CC(NC(=O)CCCC[C@]23CCC(C)(C)C[C@H]2C2=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]4(C)[C@]2(C)CC3)C(O)=O)c1 |r,t:25| | ||
Structure |