| Reaction Details |
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 | Report a problem with these data |
| Target | Neuropeptide Y receptor type 5 |
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| Ligand | BDBM50265296 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_496407 (CHEMBL1001157) |
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| IC50 | 19±n/a nM |
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| Citation |  Ogino, Y; Ohtake, N; Nagae, Y; Matsuda, K; Moriya, M; Suga, T; Ishikawa, M; Kanesaka, M; Mitobe, Y; Ito, J; Kanno, T; Ishihara, A; Iwaasa, H; Ohe, T; Kanatani, A; Fukami, T Design, syntheses, and structure-activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4'-piperidin]-1'-yl}benzimidazole derivatives. Bioorg Med Chem Lett18:5010-4 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Neuropeptide Y receptor type 5 |
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| Name: | Neuropeptide Y receptor type 5 |
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| Synonyms: | NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor |
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| Type: | Enzyme |
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| Mol. Mass.: | 50746.64 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15761 |
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| Residue: | 445 |
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| Sequence: | MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNL
LILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFL
QCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSL
VELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISC
GLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAP
ERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIK
KRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCL
NPILYGFLNNGIKADLVSLIHCLHM
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| BDBM50265296 |
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| n/a |
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| Name | BDBM50265296 |
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| Synonyms: | 2-(3-oxo-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)-1H-benzo[d]imidazole-5-carbonitrile | CHEMBL521720 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16N4O2 |
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| Mol. Mass. | 344.3666 |
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| SMILES | O=C1OC2(CCN(CC2)c2nc3ccc(cc3[nH]2)C#N)c2ccccc12 |
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| Structure | 
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