| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Transcriptional activator protein TraR |
|---|
| Ligand | BDBM50266237 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_543882 (CHEMBL1016857) |
|---|
| IC50 | 2400±n/a nM |
|---|
| Citation |  Geske, GD; Mattmann, ME; Blackwell, HE Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. Bioorg Med Chem Lett18:5978-81 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Transcriptional activator protein TraR |
|---|
| Name: | Transcriptional activator protein TraR |
|---|
| Synonyms: | TRAR_RHIRD | traR |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 26741.83 |
|---|
| Organism: | Rhizobium radiobacter |
|---|
| Description: | ChEMBL_765233 |
|---|
| Residue: | 234 |
|---|
| Sequence: | MQHWLDKLTDLAAIEGDECILKTGLADIADHFGFTGYAYLHIQHRHITAVTNYHRQWQST
YFDKKFEALDPVVKRARSRKHIFTWSGEHERPTLSKDERAFYDHASDFGIRSGITIPIKT
ANGFMSMFTMASDKPVIDLDREIDAVAAAATIGQIHARISFLRTTPTAEDAAWLDPKEAT
YLRWIAVGKTMEEIADVEGVKYNSVRVKLREAMKRFDVRSKAHLTALAIRRKLI
|
|
|
|---|
| BDBM50266237 |
|---|
| n/a |
|---|
| Name | BDBM50266237 |
|---|
| Synonyms: | (S)-2-(3,4-dichlorophenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide | CHEMBL509975 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H11Cl2NO3 |
|---|
| Mol. Mass. | 288.127 |
|---|
| SMILES | Clc1ccc(CC(=O)N[C@H]2CCOC2=O)cc1Cl |r| |
|---|
| Structure | 
|
|---|
Search and Browse
