| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Calpain-2 catalytic subunit |
|---|
| Ligand | BDBM50263558 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_535802 (CHEMBL991567) |
|---|
| IC50 | 190±n/a nM |
|---|
| Citation |  Shirasaki, Y; Takahashi, H; Yamaguchi, M; Inoue, J Molecular design to enhance the penetration into the retina via ocular instillation. Bioorg Med Chem Lett18:5174-7 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Calpain-2 catalytic subunit |
|---|
| Name: | Calpain-2 catalytic subunit |
|---|
| Synonyms: | 3.4.22.53 | CAN2_PIG | CANP 2 | CAPN2 | Calcium-activated neutral proteinase 2 | Calpain 2 | Calpain M-type | Calpain-2 catalytic subunit | Calpain-2 large subunit | M-calpain | Millimolar-calpain |
|---|
| Type: | n/a |
|---|
| Mol. Mass.: | 37789.71 |
|---|
| Organism: | Sus scrofa |
|---|
| Description: | n/a |
|---|
| Residue: | 324 |
|---|
| Sequence: | YPNTFWMNPQYLIKLEEEDEDQEDGESGCTFLVGLIQKHRRRQRKMGEDMHTIGFGIYEV
PEELTGQTNIHLSKNFFLTHRARERSDTFINLREVLNRFKLPPGEYILVPSTFEPNKDGD
FCIRVFSEKKADYQVVDDEIEADLEENDASEDDIDDGFRRLFAQLAGEDAEISAFELQTI
LRRVLAKRQDIKSDGFSIETCRIMVDMLDSDGSAKLGLKEFYILWTKIQKYQKIYREIDV
DRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDQLIIDFDNFVRCLVRLETLFRIS
KQLDSENTGTIELDLISWLCFSVL
|
|
|
|---|
| BDBM50263558 |
|---|
| n/a |
|---|
| Name | BDBM50263558 |
|---|
| Synonyms: | 2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)ethyl (S)-1-((S)-4-(cyclopropylamino)-3,4-dioxo-1-phenylbutan-2-ylamino)-4-methyl-1-oxopentan-2-ylcarbamate | CHEMBL455277 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H49N3O10 |
|---|
| Mol. Mass. | 623.7349 |
|---|
| SMILES | COCCOCCOCCOCCOCCOC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)C(=O)NC1CC1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
