| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform gamma-1 |
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| Ligand | BDBM50094893 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_535968 (CHEMBL987142) |
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| IC50 | 26200±n/a nM |
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| Citation |  Cozza, G; Gianoncelli, A; Montopoli, M; Caparrotta, L; Venerando, A; Meggio, F; Pinna, LA; Zagotto, G; Moro, S Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening. Bioorg Med Chem Lett18:5672-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform gamma-1 |
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| Name: | Casein kinase I isoform gamma-1 |
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| Synonyms: | CKI-gamma 1 | CSNK1G1 | Casein kinase I | Casein kinase I gamma 1 isoform | Casein kinase I isoform gamma-1 | KC1G1_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 48530.93 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_774608 |
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| Residue: | 422 |
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| Sequence: | MDHPSREKDERQRTTKPMAQRSAHCSRPSGSSSSSGVLMVGPNFRVGKKIGCGNFGELRL
GKNLYTNEYVAIKLEPIKSRAPQLHLEYRFYKQLGSAGEGLPQVYYFGPCGKYNAMVLEL
LGPSLEDLFDLCDRTFTLKTVLMIAIQLLSRMEYVHSKNLIYRDVKPENFLIGRQGNKKE
HVIHIIDFGLAKEYIDPETKKHIPYREHKSLTGTARYMSINTHLGKEQSRRDDLEALGHM
FMYFLRGSLPWQGLKADTLKERYQKIGDTKRNTPIEALCENFPEEMATYLRYVRRLDFFE
KPDYEYLRTLFTDLFEKKGYTFDYAYDWVGRPIPTPVGSVHVDSGASAITRESHTHRDRP
SQQQPLRNQVVSSTNGELNVDDPTGAHSNAPITAHAEVEVVEEAKCCCFFKRKRKKTAQR
HK
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| BDBM50094893 |
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| n/a |
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| Name | BDBM50094893 |
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| Synonyms: | 1-Amino-4-hydroxy-anthraquinone | 1-hydroxy-4-amino-anthraquinone | CHEMBL88326 | cid_8323 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9NO3 |
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| Mol. Mass. | 239.2262 |
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| SMILES | Nc1ccc(O)c2C(=O)c3ccccc3C(=O)c12 |
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| Structure | 
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