| Reaction Details |
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 | Report a problem with these data |
| Target | Casein kinase I isoform alpha |
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| Ligand | BDBM50094893 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_535969 (CHEMBL987143) |
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| IC50 | 4000±n/a nM |
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| Citation |  Cozza, G; Gianoncelli, A; Montopoli, M; Caparrotta, L; Venerando, A; Meggio, F; Pinna, LA; Zagotto, G; Moro, S Identification of novel protein kinase CK1 delta (CK1delta) inhibitors through structure-based virtual screening. Bioorg Med Chem Lett18:5672-5 (2008) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Casein kinase I isoform alpha |
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| Name: | Casein kinase I isoform alpha |
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| Synonyms: | CK1 | CKI-alpha | CSNK1A1 | Casein Kinase I | Casein kinase 1 alpha (CK1 alpha) | Casein kinase I isoform alpha/delta | KC1A_HUMAN |
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| Type: | Serine/threonine-protein kinase |
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| Mol. Mass.: | 38936.59 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48729 |
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| Residue: | 337 |
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| Sequence: | MASSSGSKAEFIVGGKYKLVRKIGSGSFGDIYLAINITNGEEVAVKLESQKARHPQLLYE
SKLYKILQGGVGIPHIRWYGQEKDYNVLVMDLLGPSLEDLFNFCSRRFTMKTVLMLADQM
ISRIEYVHTKNFIHRDIKPDNFLMGIGRHCNKLFLIDFGLAKKYRDNRTRQHIPYREDKN
LTGTARYASINAHLGIEQSRRDDMESLGYVLMYFNRTSLPWQGLKAATKKQKYEKISEKK
MSTPVEVLCKGFPAEFAMYLNYCRGLRFEEAPDYMYLRQLFRILFRTLNHQYDYTFDWTM
LKQKAAQQAASSSGQGQQAQTPTGKQTDKTKSNMKGF
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| BDBM50094893 |
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| n/a |
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| Name | BDBM50094893 |
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| Synonyms: | 1-Amino-4-hydroxy-anthraquinone | 1-hydroxy-4-amino-anthraquinone | CHEMBL88326 | cid_8323 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H9NO3 |
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| Mol. Mass. | 239.2262 |
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| SMILES | Nc1ccc(O)c2C(=O)c3ccccc3C(=O)c12 |
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| Structure | 
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