| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50253086 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_539776 (CHEMBL1034994) |
|---|
| Ki | 93±n/a nM |
|---|
| Citation |  Leopoldo, M; Lacivita, E; De Giorgio, P; Fracasso, C; Guzzetti, S; Caccia, S; Contino, M; Colabufo, NA; Berardi, F; Perrone, R Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides: influence on lipophilicity and 5-HT7 receptor activity. Part III. J Med Chem51:5813-22 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | D(2) dopamine receptor | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2 | DRD2_HUMAN | Dopamine D2 receptor | Dopamine D2 receptor (D2) | Dopamine D2 receptor (D2R) | Dopamine D2A | Dopamine2-like | d2 |
|---|
| Type: | Cell-surface receptors |
|---|
| Mol. Mass.: | 50647.10 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P14416 |
|---|
| Residue: | 443 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSDGKADRPHYNYYATLLTLLIAVIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMISIVWVLSFTISCPLLFGLNNADQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRRRRKRVNTKRSSRAFRAHLRAPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRVEAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSTPDSPAKPEKNGHAKDHPKIAKIFEIQTMPNGKTRTSLKTMSR
RKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSA
VNPIIYTTFNIEFRKAFLKILHC
|
|
|
|---|
| BDBM50253086 |
|---|
| n/a |
|---|
| Name | BDBM50253086 |
|---|
| Synonyms: | 2-[6-[4-(2-Diphenyl)-1-piperazinyl]-1-oxohexyl]isoindoline | CHEMBL494118 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C30H35N3O |
|---|
| Mol. Mass. | 453.6184 |
|---|
| SMILES | O=C(CCCCCN1CCN(CC1)c1ccccc1-c1ccccc1)N1Cc2ccccc2C1 |
|---|
| Structure | 
|
|---|
Search and Browse
