| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Gag polyprotein |
|---|
| Ligand | BDBM50240439 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_536774 (CHEMBL984568) |
|---|
| IC50 | 7500±n/a nM |
|---|
| Citation |  LaFrate, AL; Gunther, JR; Carlson, KE; Katzenellenbogen, JA Synthesis and biological evaluation of guanylhydrazone coactivator binding inhibitors for the estrogen receptor. Bioorg Med Chem16:10075-84 (2008) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Gag polyprotein |
|---|
| Name: | Gag polyprotein |
|---|
| Synonyms: | GAG_AVIER | gag |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 61664.68 |
|---|
| Organism: | Avian erythroblastosis virus (strain ES4) |
|---|
| Description: | ChEMBL_536774 |
|---|
| Residue: | 555 |
|---|
| Sequence: | REEQVTSEQAKFWLGLGGGRVSPPGPECIEKPATERRIDKGEEMGETTVQRDAKMAPEKM
ATPKTVGTSCYQCGTATGCNCVTASAPPPPYVGSGLYPSLAGAGEQGQGGDTPRGAEQPR
AEPGHAGQAPGPALTDWARIREELASTGPPVVAMPVVIKTEGPAWTPLEPEDTRWLDGKH
KRKSSQCLVKSSMSGYIPSCLDKDEQCVVCGDKATGYHYRCITCEGCKSFFRRTIQKNLH
PTYSCTYDGCCVIDKITRNQCQLCRFKKCISVGMAMDLVLDDSKRVAKRKLIEENRERRR
KEEMIKSLQHRPSPSAEEWELIHVVTEAHRSTNAQGSHWKQRRKFLLEDIGQSPMASMLD
GDKVDLEAFSEFTKIITPAITRVVDFAKNLPMFSELPCEDQIILLKGCCMEIMSLRAAVR
YDPESETLTLSGEMAVKREQLKNGGLGVVSDAIFDLGKSLSAFNLDDTEVALLQAVLLMS
SDRTGLICVDKIEKCQESYLLAFEHYINYRKHNIPHFWSKLLMKVADLRMIGAYHASRFL
HMKVECPTELSPQEV
|
|
|
|---|
| BDBM50240439 |
|---|
| n/a |
|---|
| Name | BDBM50240439 |
|---|
| Synonyms: | 2-(1-Naphthalenylmethylene) hydrazinecarboximidamide | CHEMBL33663 | N''-[(1E)-1-naphthylmethylene]carbonohydrazonic diamide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H12N4 |
|---|
| Mol. Mass. | 212.2505 |
|---|
| SMILES | [#7]\[#6](-[#7])=[#7]\[#7]=[#6]-c1cccc2ccccc12 |w:5.5| |
|---|
| Structure | 
|
|---|
Search and Browse
